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What is Staphylococcus aureus known for?
It is an important hospital pathogen.
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What are the learning outcomes regarding Staphylococcus aureus?
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What should be done before the in-person sessions?
Read resources on Canvas and fill in summary notes.
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What is the focus of Session 1?
Current knowledge of Staphylococcus aureus as a hospital pathogen.
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What is a risk factor associated with Staphylococcus aureus?
Carriage of S. aureus.
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What is discussed in Session 2?
Future treatments of Staphylococcus aureus.
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What model is used for studying S. aureus infection?
Bacteriophage rabbit wound model.
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What is Helicobacter pylori associated with?
Diseases caused by H. pylori and gastric adenocarcinoma.
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What are key characteristics of Helicobacter pylori?
Present in most mammals and partially fulfills Koch’s postulates.
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What is a major virulence factor of H. pylori?
Urease, which facilitates gastric colonization.
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What does the Type IV Secretion System in H. pylori do?
It is involved in virulence factors like CagA, a known bacterial oncoprotein.
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What is Neisseria gonorrhoeae known for?
It is the causative agent of gonorrhoea, a bacterial STI.
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What is the global impact of STIs?
Significant public health concern affecting populations worldwide.
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What are the symptoms of gonorrhoea?
Symptoms can include painful urination and discharge.
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What is included in the standard treatment for gonorrhoea?
Antibiotics are used for treatment.
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What is the first step in Norrhoeae infection?
Adherence: close interaction with host cells
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What structure is involved in adherence for Norrhoeae?
Type IV pili
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What protein is involved in attachment during Norrhoeae infection?
Opacity A (OpA) protein
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What molecules are involved in internalization for Norrhoeae?
LOS & sialylation
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What enzyme is involved in transcytosis for Norrhoeae?
IgA protease
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What helps Norrhoeae to survive in neutrophils?
Porin: immuno-dominant antigen
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What is a multifunctional virulence factor for Norrhoeae?
Porin
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How does porin affect complement pathways?
Blocks activation of complement pathways
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What is the sixth step in Norrhoeae infection?
Enter blood stream
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What are Norrhoeae classified as in terms of STIs?
Emerging superbugs
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What is increasing in New Zealand regarding Norrhoeae?
Antimicrobial resistance
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What is the timeline for Norrhoeae?
Gonococci: Timeline of antimicrobial resistance
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What is a breakthrough in treating gonorrhoea?
New antibiotic for gonorrhoea
Parcoures tes cartes ici, ou sign up to study with spaced repetition.
What should everyone do regarding Norrhoeae?
Stay safe everyone
Parcoures tes cartes ici, ou sign up to study with spaced repetition.
What is Staphylococcus aureus known for?
It is an important hospital pathogen.
What are the learning outcomes regarding Staphylococcus aureus?
What should be done before the in-person sessions?
Read resources on Canvas and fill in summary notes.
What is the focus of Session 1?
Current knowledge of Staphylococcus aureus as a hospital pathogen.
What is a risk factor associated with Staphylococcus aureus?
Carriage of S. aureus.
What is discussed in Session 2?
Future treatments of Staphylococcus aureus.
What model is used for studying S. aureus infection?
Bacteriophage rabbit wound model.
What is Helicobacter pylori associated with?
Diseases caused by H. pylori and gastric adenocarcinoma.
What are key characteristics of Helicobacter pylori?
Present in most mammals and partially fulfills Koch’s postulates.
What is a major virulence factor of H. pylori?
Urease, which facilitates gastric colonization.
What does the Type IV Secretion System in H. pylori do?
It is involved in virulence factors like CagA, a known bacterial oncoprotein.
What is Neisseria gonorrhoeae known for?
It is the causative agent of gonorrhoea, a bacterial STI.
What is the global impact of STIs?
Significant public health concern affecting populations worldwide.
What are the symptoms of gonorrhoea?
Symptoms can include painful urination and discharge.
What is included in the standard treatment for gonorrhoea?
Antibiotics are used for treatment.
What is the first step in Norrhoeae infection?
Adherence: close interaction with host cells
What structure is involved in adherence for Norrhoeae?
Type IV pili
What protein is involved in attachment during Norrhoeae infection?
Opacity A (OpA) protein
What molecules are involved in internalization for Norrhoeae?
LOS & sialylation
What enzyme is involved in transcytosis for Norrhoeae?
IgA protease
What helps Norrhoeae to survive in neutrophils?
Porin: immuno-dominant antigen
What is a multifunctional virulence factor for Norrhoeae?
Porin
How does porin affect complement pathways?
Blocks activation of complement pathways
What is the sixth step in Norrhoeae infection?
Enter blood stream
What are Norrhoeae classified as in terms of STIs?
Emerging superbugs
What is increasing in New Zealand regarding Norrhoeae?
Antimicrobial resistance
What is the timeline for Norrhoeae?
Gonococci: Timeline of antimicrobial resistance
What is a breakthrough in treating gonorrhoea?
New antibiotic for gonorrhoea
What should everyone do regarding Norrhoeae?
Stay safe everyone
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