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Flashcards in this deck (121)
  • What is the first step in the vision pathway?

    Retina (nasal or temporal half)

    neuroscience vision
  • What follows the retina in the vision pathway?

    Optic nerve (through optic canal)

    neuroscience vision
  • What is the third component of the vision pathway?

    Optic chiasm

    neuroscience vision
  • After the optic chiasm, what is the next part in the vision pathway?

    Optic tract

    neuroscience vision
  • What part of the thalamus is involved in the vision pathway?

    Lateral geniculate nucleus of thalamus

    neuroscience vision
  • What comes after the lateral geniculate nucleus in the vision pathway?

    Optic radiation

    neuroscience vision
  • Where does the vision pathway end?

    Occipital lobe's visual cortex

    neuroscience vision
  • What visual information travels from the retina to the visual cortex?

    Information flows from the retina through the optic nerve, chiasm, tract, lateral geniculate nucleus, optic radiation, to the visual cortex.

    neuroscience vision
  • What does the optic chiasm do?

    It allows nasal visual information to cross, entering the contralateral optic tract.

    neuroscience vision
  • How does information from the temporal side of the visual field travel?

    It enters the ipsilateral optic tract.

    neuroscience vision
  • Describe the path of nasal visual information.

    It crosses at the optic chiasm and enters the contralateral optic tract.

    neuroscience vision
  • What happens to visual fields during processing?

    They converge at the optic chiasm, allowing for visual integration.

    neuroscience vision
  • What visual loss occurs with an optic nerve lesion?

    Visual loss in one eye

    vision anatomy
  • What is the result of an optic chiasm lesion?

    Bitemporal hemianopia 3!

    vision anatomy
  • What vision deficit is associated with lesions in optic radiation or occipital lobe?

    Contralateral homonymous hemianopia 6,7

    vision anatomy
  • What is an ipsilateral monocular scotoma?

    Visual field deficit in one eye

    vision anatomy
  • What does bitemporal hemianopia indicate?

    Loss of peripheral vision in both eyes

    vision anatomy
  • What does bilateral central scotoma indicate?

    Loss of central vision in both eyes

    vision anatomy
  • When does the development of the eye begin?

    In the 4th week of development.

    development anatomy
  • What forms the retina during eye development?

    It forms from the developing brain.

    development retina
  • What extends from the developing diencephalon?

    The optic vesicles.

    anatomy diencephalon
  • What does the optic cup form?

    It forms a double layered neural tunic And anterior surface

    anatomy optic_cup
  • What does the optic stalk become?

    It becomes the optic nerve.

    anatomy optic_nerve
  • What induces the formation of the lens in eye development?

    Overlying ectoderm forms lens pit, inducing lens formation.

    embryology eye
  • From what does the sclera and choroid develop?

    They form from mesenchyme surrounding the optic cup.

    embryology eye
  • What does the choroid give rise to?

    • Iris
    • Ciliary body
    • Suspensory ligaments
    embryology eye
  • What tissues form the eyelids, conjunctiva, and cornea?

    Surrounding mesenchyme and ectoderm.

    embryology eye
  • What is the function of the external ear?

    Transfer of sound - Bound internally by tympanic membrane

    anatomy ear senses
  • What connects the middle ear to the nasopharynx?

    Pharyngotympanic tube

    anatomy ear senses
  • What does the internal ear transfer to the CNS?

    Sound

    anatomy ear senses
  • What sensations are produced by fluid movement in the internal ear?

    • Hearing
    • Equilibrium (balance)
    anatomy ear senses
  • What is the external ear primarily composed of?

    • Elastic cartilage
    • Temporal bone
    • auricle (pinna)
    • External acoustic meatus: Outside-ear-hole, Contains ceruminous (produce cerumen/earwax) and sebaceous glands
    • Tympanic membrane (ear drum): Oriented like a mini radar or satellite dish to receive sound waves
    anatomy ear
  • What is the function of the tympanic membrane?

    Receives sound waves

    anatomy ear
  • What does the external acoustic meatus contain?

    • Ceruminous glands (produce earwax)
    • Sebaceous glands
    anatomy ear
  • What does the middle ear consist of?

    • Tympanic cavity: Lined with mucous membrane
    • openings: mastoid air cells, pharyngotympanic tube (Eustachian tube/auditory tube)
    • ear bones (malleus, incus, stapes)
    anatomy ear
  • What is the function of the pharyngotympanic tube?

    Equalizes pressure in the middle ear

    anatomy ear
  • What structure allows the pharyngotympanic tube to open?

    Muscle contraction in the soft palate

    anatomy ear
  • What are the openings in the middle ear?

    • Mastoid air cells
    • Pharyngotympanic tube
    anatomy ear
  • What is the anatomical role of the tympanic membrane?

    Oriented to receive sound (like radar dish)

    anatomy ear
  • What connects the middle ear to the nasal cavity?

    Pharyngotympanic tube

    anatomy ear
  • Which structure in the middle ear is responsible for pressure equalization?

    Pharyngotympanic tube

    anatomy ear
  • What are the auditory ossicles in the middle ear?

    • Malleus (hammer)
    • Incus (anvil)
    • Stapes (stirrup)
    anatomy middle_ear
  • What is the function of the malleus?

    Moves with the tympanic membrane.

    anatomy physiology
  • What is the function of the stapes?

    Connects to the oval window.

    anatomy physiology
  • How does the base of the stapes compare to the tympanic membrane?

    Its base is smaller than the tympanic membrane, increasing vibratory force by 10x.

    anatomy physics
  • What is the function of the Stapedius muscle?

    Prevents excessive movement of the stapes.

    anatomy middle_ear
  • What does the Tensor tympani muscle do?

    Reduces amplitude to prevent damage.

    anatomy middle_ear
  • Which cranial nerve provides the Chorda tympani nerve?

    Branch of CN VII.

    anatomy nerves
  • Which cranial nerve is part of the Tympanic plexus?

    From CN IX.

    anatomy nerves
  • What organ is contained in the inner ear?

    Vestibulocochlear organ

    anatomy ear
  • What are the functions of the vestibulocochlear organ?

    • Reception of sound
    • Maintenance of balance
    anatomy function
  • What protects the inner ear?

    Petrous part of temporal bone

    anatomy protection
  • What fluid fills the bony labyrinth?

    Perilymph

    anatomy fluid
  • What comprises the bony labyrinth?

    Surrounding cranial bone (otic capsule)

    anatomy structure
  • What fluid fills the membranous labyrinth?

    Endolymph

    anatomy fluid
  • What are the components of the bony labyrinth in the inner ear?

    • Cochlea
    • Vestibule
    • Semicircular canal
    anatomy ear inner_ear
  • What are the components of the membranous labyrinth in the inner ear?

    • Cochlear labyrinth
    • Vestibular labyrinth
    • Semicircular ducts
    anatomy ear inner_ear
  • What is the primary function of the cochlea?

    Hearing

    anatomy hearing
  • What fills the cochlea?

    Perilymph

    anatomy cochlea
  • What are the three distinct parts of the cochlea?

    • Cochlear duct
    • Scala tympani
    • Scala vestibuli
    anatomy cochlea
  • What carries the cochlear nerve within the cochlea?

    Modiolus (bony core) carries branch of CN VIII

    anatomy nerves
  • What structure does the cochlea communicate with?

    Round window containing a secondary tympanic membrane

    anatomy cochlea
  • What does the cochlear labyrinth contain?

    • Membranous structure
    • Filled with endolymph
    anatomy hearing
  • What is the cochlear labyrinth comprised of?

    • Cochlear duct
    anatomy hearing
  • Where is the spiral organ located?

    In the cochlear labyrinth

    anatomy hearing
  • What is the shape of the cochlear duct?

    Triangular in cross section

    anatomy ear
  • What is the apex of the cochlear duct called?

    Helicotrema

    anatomy ear
  • What organ sits on the basilar membrane in the cochlear duct?

    Spiral organ (organ of Corti)

    anatomy ear hearing
  • What types of cells are contained within the spiral organ?

    • Supporting cells
    • Outer hair cells
    • Inner hair cells
    anatomy ear cells
  • Which nerve synapses with the cells in the spiral organ?

    Cochlear nerve

    anatomy ear nervous_system
  • What membranes are associated with the cochlear duct?

    • Tectorial membrane
    • Basilar membrane
    anatomy ear membranes
  • What structure is involved in the hearing process found in the cochlear duct?

    Spiral organ (organ of Corti)

    anatomy ear hearing
  • What are the first steps in sound transmission?

    • Vibrations
    • Tympanic membrane
    • Ossicles
    • Base of stapes at oval window
    biology hearing
  • How do vibrations transfer into fluid in the ear?

    Vibrations transfer into hydraulic waves in perilymph of scala vestibuli

    biology hearing
  • What leads to hair cells deflection?

    Deformation of cochlear duct causes endolymph to deflect hair cells, activating cochlear nerve fibers (CN VIII)

    biology hearing
  • What happens to hydraulic waves after the cochlear duct?

    Hydraulic waves continue through to scala tympani and reach the secondary tympanic membrane in round window

    biology hearing
  • What fluid is involved in sound transmission?

    Endolymph

    anatomy audio
  • How do high frequency sounds affect the basilar membrane?

    Displace closer to the oval window (shorter distance)

    anatomy audio
  • How do low frequency sounds affect the basilar membrane?

    Displace closer to helicotrema (longer distance)

    anatomy audio
  • What follows after synapsing on cochlear nerve fibers?

    Spiral ganglion → Sound is interpreted by CNS

    anatomy audio
  • What are the steps in the auditory pathway?

    1. Hair cells in spiral organ

    2. Spiral ganglion (primary neurons)

    3. Cochlear nerve

    4. CN VIII

    5. Cochlear nuclei in brain stem (synapse- secondary neurons)

    6. Superior olivary nuclei (auditory acuity and localizing of sound)

    7. Inferior colliculi

    8. Thalamus (tertiary neurons)

    9. Primary auditory cortex in temporal lobe

    anatomy auditory
  • Which nerve is responsible for transmitting auditory signals?

    Cochlear nerve (branch of CNVIII)—> to CN VIII

    anatomy nerves
  • What is the role of the Cochlear nuclei?

    They act as secondary neurons in the brain stem.

    anatomy auditory brainstem
  • What structure helps with auditory acuity and sound localization?

    Superior olivary nuclei

    anatomy auditory brainstem
  • Which part of the brain is responsible for processing auditory information after superior olivary nuclei—> inferior colliculi?

    Thalamus (tertiary neurons)

    anatomy auditory thalamus
  • Where does the auditory perception occur in the brain?

    Primary auditory cortex in the temporal lobe

    anatomy auditory cortex
  • What type of hearing loss is linked to the external or middle ear?

    Conductive hearing loss

    hearing anatomy
  • What are examples of conductive hearing loss?

    • Otitis media
    • Cerumen impaction
    hearing examples
  • Which parts of the ear are affected in sensorineural hearing loss?

    Cochlea or CN VIII

    hearing anatomy
  • What examples are associated with sensorineural hearing loss?

    • Noise damage
    • Age
    • Drugs
    hearing examples
  • What is the location of conductive hearing loss lesions?

    External or middle ear

    hearing anatomy
  • What is the location of sensorineural hearing loss lesions?

    Cochlea or CN VIII

    hearing anatomy
  • What is the function of the vestibule?

    Balance and equilibrium

    anatomy equilibrium
  • What does the vestibule contain?

    • Utricle
    • Saccule
    anatomy vestibule
  • What is the structure of the vestibular labyrinth?

    • Utricle
    • Saccule
    anatomy vestibular_labyrinth
  • What are maculae?

    Specialized epithelium with hair cells in utricle and saccule

    anatomy maculae
  • How many semicircular canals are there?

    There are three semicircular canals.

    anatomy ear
  • What is the orientation of the semicircular canals?

    They are oriented at right angles to occupy three planes in space.

    anatomy ear
  • What is the bony ampulla?

    It's an expansion at the base of the semicircular canals.

    anatomy ear
  • What are semicircular ducts?

    They are portions of the membranous labyrinth within the semicircular canals.

    anatomy ear
  • What is contained in the ampulla of the semicircular ducts?

    Hair cells for sensation are contained in the ampulla.

    anatomy ear sensation
  • Where do the semicircular ducts open?

    They open into the utricle.

    anatomy ear
  • What nerve innervates the vestibular system?

    Vestibular nerve (branch of CN VIII)

    anatomy nervous_system
  • How does the vestibular system sense motion?

    By recording movement of endolymph via hair cells

    physiology sensation
  • What structures are sensitive to gravity and acceleration?

    Utricle and saccule

    anatomy vestibular
  • What is the specialized epithelium containing hair cells in the utricle and saccule?

    Maculae

    anatomy vestibular
  • What do hair cells project into?

    Otolithic membrane

    anatomy vestibular
  • What are the mineralized structures in the otolithic membrane?

    Otoliths

    anatomy vestibular
  • What is the function of the otolithic membrane?

    Helps in sensing gravity and linear acceleration

    physiology vestibular
  • What is the role of hair cells in the vestibular system?

    Transduce mechanical changes into neural signals

    physiology neuroscience
  • What do the ampullae contain?

    • Crista ampullaris: Contains hair cells, Projects into cupula
    anatomy inner_ear
  • What do the ampullae sense?

    • Rotational acceleration
    • Deceleration of the head
    physiology vestibular
  • How do ampullae sense rotations?

    Due to movement of endolymph in semicircular ducts

    physiology inner_ear
  • What initiates the vestibular sensation pathway?

    • Hair cells in maculae of utricle
    • Hair cells in saccule
    • Hair cells in ampulla
    anatomy vestibular
  • What represents the primary neurons in the vestibular pathway?

    • Vestibular ganglion
    anatomy vestibular
  • What is the function of the vestibular nerve?

    • Transmits information from vestibular apparatus to brain
    neuroanatomy vestibular
  • Which cranial nerve is involved in the vestibular sensation pathway?

    CN VIII

    neuroanatomy cranial_nerves
  • Where do the secondary neurons synapse in the vestibular pathway?

    Vestibular nuclei in the medulla

    anatomy vestibular
  • What is the role of the vestibulospinal tract?

    • Regulates muscle tone
    • Helps maintain balance
    physiology vestibular
  • What does the Vestibulo-Ocular Reflex (VOR) coordinate?

    • Reflexive motor activities
    • Coordinates eye (CN III and CN VI), head, and neck movements
    physiology vestibular
  • Which brain structures receive projections from vestibular signals?

    Tertiary neurons

    • Cerebellum
    • Thalamus
    • Cerebral cortex
    anatomy vestibular
Study Notes

Vision Pathway

  1. Retina (nasal or temporal half)
  2. Optic nerve (through optic canal)
  3. Optic chiasm
  4. Optic tract
  5. Lateral geniculate nucleus of thalamus
  6. Optic radiation
  7. Occipital lobe's visual cortex

Visual pathway diagram

Optic Chiasm Processing

Visual Information Processing

  • Temporal side: ipsilateral optic tract
  • Nasal side: contralateral optic tract
  • Each optic tract processes contralateral visual fields

Diagram of the optic chiasm

Visual Pathway Lesions

Visual Field Deficits

  1. Optic nerve lesion: visual loss in one eye
  2. Optic chiasm lesion: bitemporal hemianopia
  3. Optic radiation/occipital lobe lesion: contralateral homonymous hemianopia

Visual pathway lesions diagram

Development of the Eye

Key Stages

  • Begins in the 4th week of development
  • Retina forms from the developing brain
  • Optic vesicles extend from diencephalon
  • Forms the optic cup (double layered neural tunic)
  • Optic stalk becomes the optic nerve

Eye development illustrations

Parts of the Eye Development

Structures Formation

  • Lens: overlying ectoderm induces lens formation
  • Sclera & Choroid: form from mesenchyme surrounding the optic cup
  • Choroid: forms iris, ciliary body, suspensory ligaments
  • Eyelids, conjunctiva, cornea: from ectoderm and mesenchyme

Detailed eye development

Hearing and Balance Overview

Ear Structures

  • External Ear: transfers sound, bound internally by tympanic membrane
  • Middle Ear: contains ossicles, opens to nasopharynx via pharyngotympanic tube
  • Internal Ear: transfers sound to CNS; movement of fluid results in sensations of hearing and balance

Cross-section of the ear

External and Middle Ear Components

Key Features

  • External Ear Components: auricle, external acoustic meatus, tympanic membrane
  • Middle Ear Components: tympanic cavity, lined with mucous membrane
  • Openings: mastoid air cells, pharyngotympanic tube (Eustachian tube)

Ear components

Middle Ear Contents

Auditory Ossicles

  • Malleus (hammer): moves with tympanic membrane
  • Incus (anvil)
  • Stapes (stirrup): interacts with the oval window, amplifying sound

Middle ear ossicles

Inner Ear Components

Main Structures

  • Bony Labyrinth: perilymph-filled, includes cochlea, vestibule, semicircular canals
  • Membranous Labyrinth: filled with endolymph, series of sacs and ducts

Bony labyrinth diagram

Cochlear Structure

Cochlear Labyrinth Functions

  • Three Parts: cochlear duct, scala tympani, scala vestibuli
  • Modiolus: carries cochlear nerve (CN VIII) and vessels
  • Communicates with round window

Cochlear cross-section

Sound Transmission Process

  1. Vibrations → tympanic membrane
  2. Ossicles → base of stapes at oval window
  3. Hydraulic waves in perilymph → scala vestibuli
  4. Hair cell deflection → cochlear nerve (CN VIII)
  5. Waves reach the round window

Sound transmission diagram

Auditory Pathway

  1. Hair cells in spiral organ
  2. Spiral ganglion (primary neurons)
  3. Cochlear nerve
  4. CN VIII
  5. Cochlear nuclei in brainstem
  6. Superior olivary nuclei
  7. Inferior colliculi
  8. Thalamus
  9. Primary auditory cortex

Auditory pathway diagram

Clinical Connection: Hearing Loss

Type Lesion Location Example
Conductive External or middle ear Otitis media, cerumen impaction
Sensorineural Cochlea or CN VIII Noise damage, age, drugs

Hearing loss diagram

Vestibular System Overview

Key Components

  • Vestibule: contains utricle and saccule
  • Maculae: specialized epithelium with hair cells

Vestibule diagram

Semicircular Ducts and Canals

Structure and Function

  • Detect head rotation
  • Crista Ampullaris: contains hair cells for sensation

Semicircular ducts diagram

Vestibular Sensation Pathway

  1. Hair cells in maculae
  2. Vestibular ganglion (primary neurons)
  3. Vestibular nerve
  4. CN VIII
  5. Vestibular nuclei in medulla (secondary neurons)
  6. Projects to cerebellum

Vestibular pathway diagram