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Flashcards in this deck (24)
  • The vapor pressure of Sevoflurane at 20 degrees C is 170 mmHg.

    physics vaporization
  • Desflurane has a vapor pressure approximately at 669 mmHg at 20 degrees C.

    physics vaporization
  • Under the Law of Laplace, tension on the wall of a cylinder is proportional to the radius.

    physics law_of_laplace
  • According to Dalton's Law, the total pressure in a mixture of gases equals the sum of the individual pressures.

    physics dalton's_law
  • In Poiseuille's Law, flow rate (Q) increases by the fourth power of the radius.

    physics poiseuille's_law
  • LAMINAR FLOW is determined by viscosity when all other factors are constant.

    physics fluid_dynamics
  • Turbulent flow is primarily affected by the density of the fluid when other factors are constant.

    physics fluid_dynamics
  • The formula for flow rate, according to Poiseuille's Law, is given by \(\(Q = \frac{\pi P r^4}{8\eta L}\)\).

    physics poiseuille's_law
  • According to Henry's law, the partial pressure of an anesthetic agent in the blood is proportional to the partial pressure of the volatile in the alveoli.

    gas_laws henry's_law
  • The amount of dissolved O2 in blood can be calculated as .003 mL/100mL/mmHg.

    gas_laws o2
  • According to Charles Law, at constant pressure, volume and temperature are directly proportional.

    gas_laws charles_law
  • In Gay-Lussac's Law, pressure and temperature are directly proportional at constant volume.

    gas_laws gay-lussac's_law
  • Boyle's Gas Law describes that pressure and volume are inversely proportional at constant temperature.

    gas_laws boyle's_law
  • Fick's Law of Diffusion states that the rate of diffusion is directly proportional to partial pressure gradient, membrane area, and solubility of gas.

    diffusion fick's_law
  • According to Fick's Law, diffusion is indirectly proportional to membrane thickness and the square root of molecular weight.

    diffusion fick's_law
  • Diffusion hypoxia occurs due to high inspired % of nitrous oxide leading to hypoventilation and displacement of O2.

    diffusion gas_laws
  • In the mnemonic 'Could These Girls Possibly Be Virgins', each letter represents a different gas law including Charles Law and Boyle's law.

    mnemonic gas_laws
  • The components of the High Pressure system in an anesthesia machine include: - Hanger yoke - Yoke block with check valves - Cylinder pressure gauge - Cylinder pressure regulators.

    anesthesia machine pressure
  • The Intermediate Pressure system in an anesthesia machine starts at the pipeline and ends at the flowmeter valves.

    anesthesia machine pressure
  • Components of the Intermediate Pressure system include: - Pipeline inlets - Pressure gauges - Oxygen pressure failure device - Oxygen second stage regulator - Oxygen flush valve - Ventilator power inlet - Flowmeter valves.

    anesthesia machine pressure
  • The Low Pressure system begins at the flowmeter tubes and ends at the common gas outlet.

    anesthesia machine pressure
  • Components of the Low Pressure system include: - Flowmeter tubes (Thorpe tubes) - Vaporizers - Check valve (if present) - Common gas outlet.

    anesthesia machine pressure
  • The components of the anesthesia machine are divided into three pressure systems: High Pressure, Intermediate Pressure, and Low Pressure.

    anesthesia machine pressure
  • This table provides an overview of the anesthesia machine's pressure systems. Components Table

    anesthesia machine overview
Study Notes

MODULE 1: PHYSICS / EQUIP & MONITORING / NMJ & MUSCLE RELAXANTS

PHYSICS

I. Vaporization

Vapor Pressures at 20°C

Anesthetic Agent Vapor Pressure (mmHg)
Sevoflurane 170
Isoflurane 240
Enflurane 172
Halothane 244
Desflurane 669
  • Vapor Pressure (VP): Increases with temperature; Desflurane vaporizer operates at ~2 atm (approx. 1500 mmHg).
  • High-Low Relationships:
  • H-L-H: Higher VP agent in lower VP vaporizer results in higher delivered concentration.
  • L-H-L: Lower VP agent in higher VP vaporizer results in lower delivered concentration.
  • Latent Heat of Vaporization: Energy lost during vaporization without temperature change.

II. Pressure & Tension

  • Pressure Conversions:
  • 1 mmHg = 1.36 cmH2O, 1 atm = 760 mmHg = 101 kPa
  • Law of Laplace: Tension (\(T\)) on wall of a cylinder is proportional to its radius (\(r\)): \(\(T = P imes r\)\).
  • Dalton's Law: Total pressure is the sum of individual gas pressures.

III. Fluid Dynamics

Poiseuille's Law

  • Describes how flow rate (\(Q\)) is influenced by radius (\(r\)), pressure (\(P\)), viscosity ($ ext{η}\(), and length (\)L$). \(\(Q = rac{ ext{π}Pr^4}{8 ext{η}L}\)\).

  • Laminar Flow: Flow determined by viscosity; to increase flow:

  • Decrease needle gauge
  • Shorten needle
  • Raise IV pole.
  • Turbulent Flow: Flow determined by density; helium used with O2 to decrease turbulence during upper airway obstruction.

IV. Solubility of Gases

  • Henry's Law: Partial pressure of an anesthetic agent in blood is proportional to its alveolar pressure. Calculation example for dissolved gases in blood:
  • Dissolved O2: 0.003 mL/100mL/mmHg
  • Dissolved CO2: 0.067 mL/100mL/mmHg.

V. Gas Laws

  • Charles's Law: \(V_1/T_1 = V_2/T_2\); volume and temperature are directly proportional at constant pressure.
  • Gay-Lussac's Law: \(P/T = K\); pressure and temperature are directly proportional at constant volume.
  • Boyle's Law: \(PV = K\); pressure and volume are inversely proportional at constant temperature.
  • Fick's Law of Diffusion: Rate of diffusion is directly proportional to partial pressure gradient, membrane area, and gas solubility; inversely proportional to thickness and square root of molecular weight.

VI. Equipment & Monitoring

Anesthesia Machine Overview

  • High, Intermediate, and Low Pressure systems:
Pressure System Location Components
High Pressure Begins at the cylinder Cylinder gauges, regulators
Intermediate Pipeline to flowmeter Pressure gauges, flowmeter valves
Low Pressure Flowmeter to gas outlet Vaporizers, common gas outlet

Additional Visuals

  • Anesthesia Machine Diagram - Provides component overview of an anesthesia machine.
  • Pressure Systems Table - Describes different pressure systems in anesthesia machines.

Memory Tasks

  • Essential readings from key sources.
  • Key formulas and their applications in clinical practice.
  • Understanding anesthesia machine components and functionalities.