What is the most common neurologic complication of sickle cell disease in children?
Ischemic stroke
What triad defines acute chest syndrome in SCD?
What triggers aplast crisis in sickle cell patients?
Parvovirus B19 infection
What renal complication results from sickling in the vasa recta and causes polyuria in SCD patients?
Hyposthenuria
What is the most serious ophthalmologic complication of SCD?
Proliferative retinopathy leading to retinal detachment
What is the most common pathogen causing osteomyelitis in SCD?
Salmonella species
What causes pigment gallstones in SCD patients?
Chronic hemolysis
Why are patients with SCD prone to infections with encapsulated organisms?
Functional asplenia due to repeated splenic infarcts
What does ACS stand for in SCD patients?
Acute Chest Syndrome
What is a mnemonic for ACS in SCD?
SICKLE
What does SOB stand for in ACS symptoms?
Shortness of Breath
What might be seen on a CXR in ACS?
Infiltrate
What is a common symptom of ACS related to breathing?
Dyspnea
What symptom might indicate ACS related to lung sounds?
Krackles (crackles/rales)
What is a common oxygen saturation finding in ACS?
Low O₂ saturation
What is a common temperature finding in ACS?
Elevated temp (fever)
What renal complication results from sickling in the vasa recta and causes polyuria in SCD patients?
Hyposthenuria
What is the most serious ophthalmologic complication of SCD?
Proliferative retinopathy leading to retinal detachment
Why are patients with SCD prone to infections with encapsulated organisms?
Functional asplenia due to repeated splenic infarcts
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