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Flashcards in this deck (67)
  • Aspirin is not indicated as primary prevention of atherosclerosis for those aged < 50 due to increased risk of bleeding outweighing the cardioprotective benefit.

    medication atherosclerosis prevention
  • Mixed Connective Tissue Disease (MCTD) includes components such as SLE, systemic sclerosis, polymyositis, and RA.

    mctd autoimmune disease
  • Treat neutropenic fever (ANC < 500) with pip-tazo or cefepime for Pseudomonas coverage.

    treatment neutropenia infection
  • Myasthenia crisis is characterized by respiratory muscle weakness and often occurs after stressors like infection, surgery, or tapering off immunosuppressants.

    myasthenia crisis respiratory
  • To treat myasthenia crisis, use intubation, PLEX, or IVIg + CS.

    treatment myasthenia crisis
  • Hold AChE inhibitors during a myasthenia crisis to reduce airway secretions and risk of aspiration.

    myasthenia medication treatment
  • Medications that prolong QRS include TCAs, Class I antiarrhythmics, and amiodarone.

    medication qrs arrhythmia
  • To manage TCA overdose, use sodium bicarbonate.

    treatment tca overdose
  • "Some Risky Meds Can Prolong QT" includes Sotalol, Risperidone, Macrolides, Chloroquine, Protease inhibitors, Quinidine, and Thiazides.

    medication qt prolongation
  • "High amplitude jugular venous pulsations" denote cannon A waves indicating increased right atrial pressure.

    cardiology jvp hemodynamics
  • Pulmonary artery systolic pressure is elevated in cor pulmonale.

    cardiology pulmonary pressure
  • Cor pulmonale is caused by pHTN that may result from underlying diseases such as COPD or OSA.

    cor_pulmonale pulmonary hypertension
  • Miliary is associated with primary adrenal insufficiency.

    adrenal insufficiency condition
  • Actinic keratosis presents as sandpaper-like papules/plaques, serving as a precursor to SCC.

    dermatology skin
  • Management of actinic keratosis: cryotherapy for individual lesions, topical 5-FU for diffuse cases.

    dermatology treatment
  • Diagnosis of CLL is completed via flow cytometry of peripheral blood.

    hematology diagnostics
  • CLL often presents with cervical, supraclavicular, and axillary lymphadenopathy.

    hematology cll
  • In CLL, the presence of smudge cells on blood smear is characteristic.

    hematology cll
  • Worse prognosis of CLL is associated with multiple chain LAD, hepatosplenomegaly, and anemia/thrombocytopenia.

    hematology prognosis
  • LN biopsy is used to diagnose Hodgkin lymphoma and NHL.

    oncology diagnostics
  • LV aneurysm results from scarring of the LV wall, leading to heart failure, arrhythmias, and secondary mitral regurgitation.

    cardiology lv_aneurysm
  • Infective endocarditis can cause dyspnea, cough, and edema, normocytic anemia, and 2º heart failure with elevated ESR.

    cardiology infective_endocarditis
  • Confirm the diagnosis of IE with blood cultures and an echo showing valvular lesions.

    cardiology diagnostics
  • Pulsus paradoxus can indicate conditions like tamponade, asthma, and COPD.

    cardiology signs
  • Digoxin toxicity can present with gastrointestinal symptoms, weakness, confusion, and visual changes.

    pharmacology toxicity
  • Transfusion anaphylaxis occurs within seconds, while TRALI takes minutes to hours.

    hematology transfusion
  • TRALI is characterized by donor anti-leukocyte antibodies causing pulmonary edema with bilateral pulmonary infiltrates.

    pulmonology trali
  • Normal values are: PaCO2 35–45 mmHg and PaO2 80–100 mmHg.

    pulmonology normal_values
  • Chronic low back pain with a restrictive pattern suggests ankylosing spondylitis affecting chest wall motion.

    rheumatology ankylosing_spondylitis
  • Cardiac sarcoidosis often presents as complete AV block, ventricular arrhythmia, and heart failure.

    cardiology sarcoidosis
  • Hyperkalemia on ECG is characterized by peaked T waves, absent/low amplitude P waves, and QRS complex widening.

    cardiology ecg
  • Sepsis causes intravascular volume depletion, potentially leading to prerenal AKI.

    nephrology sepsis
  • Coughing hard enough to cause vomiting is indicative of pertussis, which is treated with macrolide.

    pulmonology pertussis
  • APML presents with atypical promyelocytes including Auer rods and a bilobed nucleus.

    hematology apml
  • APML is associated with the chromosomal translocation t: 15, 17.

    hematology genetics
  • APML is a medical emergency due to the risk of pulmonary hemorrhage or CVA hemorrhage.

    emergency_medicine apml
  • The treatment for APML is all trans retinoic acid to promote differentiation of atypical promyelocytes.

    hematology treatment
  • Avoid using Morphine, Meperidine, Codeine, and Tramadol in patients with renal insufficiency.

    pharmacology renal
  • Stool guaiac, also known as FOBT, indicates an upper GI bleed.

    gastroenterology diagnosis
  • Milk-alkali syndrome leads to metabolic alkalosis and AKI due to increased reabsorption of bicarb.

    endocrinology renal
  • Peri-infection pericarditis occurs a few days after myocardial infarction (MI) and is triggered by transmural necrosis.

    cardiology pericarditis
  • Dressler's syndrome occurs 1 week to several months after an MI.

    cardiology dressler's_syndrome
  • HIV esophagitis is more likely to be viral if the patient has odynophagia without dysphagia.

    infectious_disease gastroenterology
  • Diagnosing HIV esophagitis involves endoscopy.

    infectious_disease diagnosis
  • IPF typically presents in ages 50-70 in smokers and those with a history of amiodarone or asbestos exposure.

    pulmonology ipf
  • Essential tremor is a bilateral action tremor that improves with EtOH.

    neurology tremors
  • Parkinson's tremor is a resting tremor that decreases with voluntary movement.

    neurology parkinson's
  • Cerebellar tremor increases as the hand approaches its target.

    neurology tremors
  • Pleuritic pain and fever suggest infectious exudate due to cytokine release causing increased vascular permeability.

    infectious_disease pathophysiology
  • To treat left heart failure resulting from pHTN, HF drugs should be utilized in patients showing hypokinesis and an EF of 30%.

    cardiology heart_failure
  • K citrate treats uric acid kidney stones by making the urine basic and promoting the solubility of the stones.

    medicine treatment kidney_stones
  • Severe seborrheic dermatitis is associated with HIV and Parkinson's.

    medicine dermatitis associations
  • SIADH is characterized by low serum osmolality and high urine osmolality with high urine sodium (>40).

    medicine siadh diagnosis
  • Mineralocorticoid deficiency presents with hyperkalemia and metabolic acidosis.

    medicine deficiency electrolytes
  • If you test positive for STI or if you are screened generally for STI test for HIV, Syphilis, NG, CT, and if women trichomonas.

    medicine sti screening
  • Both vomiting and NG tube use can cause hypochloremic metabolic alkalosis which can lead to volume depletion or prerenal AKI.

    medicine metabolic alkalosis
  • Cortisol inhibits ADH, leading to secondary Al causing slADH which causes hyponatremia.

    medicine adh hormones
  • Tuberculin skin testing > 5 is enough to treat for latent TB.

    medicine tuberculosis testing
  • Renal artery stenosis will demonstrate an upper abdominal systolic-diastolic bruit.

    medicine renal diagnosis
  • Coarctation of the aorta presents with UE HTN and LE hypotension along with delayed femoral pulses.

    medicine coarctation cardiology
  • Mycoplasma causes symptoms within 2-3 weeks, while miliary TB symptoms develop over months.

    medicine infections comparison
  • Upper GI endoscopy screening is indicated for cirrhosis to evaluate for esophageal varices.

    medicine endoscopy cirrhosis
  • Liver biopsy should be done for cirrhotic patients where there is no suspicion for underlying causes like alcoholic cirrhosis.

    medicine biopsy cirrhosis
  • C. difficile causes include recent antibiotics, hospitalization, advanced age, and using a PPI.

    medicine c._difficile causes
  • C. difficile presents with leukocytosis and fever.

    medicine c._difficile symptoms
  • SIBO is characterized by post bowel resection, postprandial diarrhea, and bloating without leukocytosis and fever.

    medicine sibo symptoms
  • ITP is marked by heavy bleeding and thrombocytopenia with normal sized and large platelets due to increased platelet turnover caused by HIV, Hep C, or underlying autoimmune conditions.

    medicine itp bleeding
Study Notes

Overview of Important Medical Conditions

This section outlines key medical conditions and their management:

  • Aspirin Use: Not for primary prevention of atherosclerosis in those < 50 due to bleeding risk.
  • Mixed Connective Tissue Disease (MCTD): Includes SLE, systemic sclerosis, polymyositis, and RA.
  • Neutropenic Fever: Treat ANC < 500 with pip-tazo or cefepime to cover Pseudomonas.
  • Myasthenia Crisis: Characterized by respiratory muscle weakness; treat with intubation, PLEX, or IVIg + CS. Hold AChE inhibitors to reduce secretions.

Medications and Cardiology

Important drug interactions and cardiovascular conditions:

  • Prolonged QRS Medications: Include TCAs, Class I antiarrhythmics, and bupropion.
  • QT Prolongation Risk: Remember "Some Risky Meds Can Prolong QT": Sotalol, Risperidone, Macrolides, Chloroquine, Protease inhibitors, Quinidine, Thiazides.
  • Cannon A Waves: Indicate high jugular venous pressure.
  • Cor Pulmonale: Caused by pulmonary hypertension due to underlying diseases like COPD and OSA.

Skin and Blood Disorders

Conditions affecting skin and hematological disorders:

  • Actinic Keratosis: Sandpaper-like lesions, precursor to SCC; treat with cryotherapy or topical FU.
  • Chronic Lymphocytic Leukemia (CLL): Diagnose via flow cytometry, presents with lymphadenopathy and smudge cells. Worse prognosis with multiple chain LAD and anemia.
  • Cardiac Arrhythmias and Conditions: Digoxin toxicity presents with gastrointestinal symptoms and confusion.

Infectious Diseases and Renal Issues

Key points regarding infectious diseases and renal conditions:

  • Infective Endocarditis (IE): Diagnosis via blood cultures + echo; causes respiratory symptoms and heart failure.
  • Sepsis and AKI: Intravenous volume depletion from sepsis can cause prerenal AKI.
  • Transfusion Reactions: Anaphylaxis occurs instantly; TRALI develops over hours.

Tumors and Hematological Emergencies

Information on critical tumor presentations and treatments:

  • Acute Promyelocytic Leukemia (APML): Characterized by atypical promyelocytes and Auer rods; urgent treatment required with all-trans retinoic acid due to hemorrhage risk.
  • Chronic versus Miliary TB: Mycoplasma infection presents quickly; miliary TB presents over months.